Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 5/20 | 0.62 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | OGG1 | O15527 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | IL1RN | P18510 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | MBTPS1 | Q14703 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548868 | 0.86 | CASP3 (0.69) | CASP3CTSDCASP1CASP8CASP7 | |
| SCHEMBL7419603 | 0.86 | CASP3 (0.69) | CASP3CTSDCASP1CASP8CASP7 | |
| SCHEMBL8547790 | 0.78 | OGG1 (0.62) | CASP3CASP1CASP8CASP7OGG1 | |
| SCHEMBL8547788 | 0.78 | OGG1 (0.62) | CASP3CASP1CASP8CASP7OGG1 | |
| SCHEMBL18831696 | 0.78 | ELANE (0.41) | CASP3CASP1ALDH1A1KDM4EHPGD | |
| SCHEMBL20305851 | 0.78 | ELANE (0.41) | CASP3CTSDCASP1ALDH1A1KDM4E | |
| SCHEMBL10208224 | 0.78 | ELANE (0.41) | CASP3CTSDCASP1ALDH1A1KDM4E | |
| SCHEMBL8544995 | 0.78 | CASP3 (0.60) | CASP3CTSDCASP1CASP8CASP7 | |
| SCHEMBL8544998 | 0.78 | CASP3 (0.60) | CASP3CTSDCASP1CASP8CASP7 | |
| SCHEMBL6813267 | 0.78 | CASP3 (0.57) | CASP3CTSDCASP1CASP8CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |