Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 12/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364844 | 0.74 | ADORA3 (0.50) | ADORA3HPRT1KDM4EGAAHPGD | |
| SCHEMBL7416914 | 0.73 | ADORA3 (0.49) | ADORA3HPRT1KDM4EHPGDRAB9A | |
| SCHEMBL7419559 | 0.69 | ADORA3 (0.48) | ADORA3HPRT1KDM4EGAAHPGD | |
| SCHEMBL7422510 | 0.69 | ADORA3 (0.48) | ADORA3HPRT1KDM4EGAAHPGD | |
| SCHEMBL21272824 | 0.68 | ADORA3 (0.51) | ADORA3HPRT1KDM4EGAAHPGD | |
| Hydrochloric Acid SCHEMBL30194697 | 0.67 | ADORA3 (0.54) | ADORA3KDM4EHPGDRAB9AHSD17B10 | |
| SCHEMBL19208631 | 0.65 | ADORA3 (0.51) | ADORA3HPRT1KDM4EGAAHPGD | |
| SCHEMBL19208420 | 0.65 | KDM4E (0.44) | ADORA3HPRT1KDM4EGAAHPGD | |
| 2-Methoxyethanol SCHEMBL7416777 | 0.63 | HPRT1 (0.36) | ADORA3HPRT1KDM4EGAAHPGD | |
| SCHEMBL7468020 | 0.61 | ADORA3 (0.66) | ADORA3HPRT1KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220856-A2 | PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Pfizer Limited (GB) | 2002-07-10 | — | — | EP | claimed |
| WO-2001027113-A2 | PYRAZOLO `4,3-d! PYRIMIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2001-04-19 | — | — | WO | claimed |