Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425515 | 0.73 | SLC6A2 (0.40) | — | |
| SCHEMBL7017472 | 0.71 | SLC6A4 (0.37) | DPP4 | |
| SCHEMBL7018597 | 0.71 | SLC6A4 (0.37) | DPP4 | |
| SCHEMBL7020799 | 0.69 | SLC6A2 (0.36) | — | |
| SCHEMBL14655544 | 0.67 | DPP4 (0.40) | DPP4 | |
| SCHEMBL1309394 | 0.66 | SLC6A4 (0.43) | — | |
| SCHEMBL7533079 | 0.65 | — | — | |
| Pivalate SCHEMBL28484105 | 0.64 | GABRP (0.39) | DPP4 | |
| Hydrochloric Acid SCHEMBL22797839 | 0.64 | SLC6A4 (0.43) | — | |
| SCHEMBL5987555 | 0.64 | PTGS1 (0.34) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001019816-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |