Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10944343 | 0.99 | TAAR1 (0.54) | TAAR1PPARAPPARGLMNAALOX15 | |
| SCHEMBL10948045 | 0.85 | PPARA (0.57) | TAAR1PPARAPPARGHTR1AMAPK1 | |
| SCHEMBL10852193 | 0.83 | TAAR1 (0.57) | TAAR1PPARAALOX15FFAR1PTPN7 | |
| Hydrochloric Acid SCHEMBL10854378 | 0.82 | TAAR1 (0.55) | TAAR1PPARAALOX15FFAR1PTPN7 | |
| Fumaric Acid SCHEMBL10946481 | 0.82 | PPARA (0.51) | TAAR1PPARAPPARGHTR1AMAPK1 | |
| Hydrochloric Acid SCHEMBL10854139 | 0.81 | TAAR1 (0.54) | TAAR1PPARAALOX15FFAR1PTPN7 | |
| SCHEMBL4416402 | 0.78 | PLA2G10 (0.64) | PPARAPPARGLMNAALOX15PLA2G10 | |
| SCHEMBL9853966 | 0.78 | TAAR1 (0.61) | TAAR1HTR1A | |
| SCHEMBL31414967 | 0.78 | TAAR1 (0.75) | TAAR1LMNAALOX15HTR1A | |
| SCHEMBL11474531 | 0.76 | TBXAS1 (0.56) | TAAR1PLA2G10PLA2G2AHTR1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4632934-A | THROMBOXANE SYNTHETASE INHIBITORS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1986-12-30 | — | — | US | disclosed |
| US-4555516-A | FOR TREATMENT OF CARDIOVASCULAR DISORDERS | PFIZER INC. (US) | 1985-11-26 | — | — | US | disclosed |
| US-4448781-A | CARDIOVASCULAR DISORDERS | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |