Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531244 | 0.83 | TAAR1 (0.50) | TAAR1GAASMN1; SMN2HTR1AHTT | |
| SCHEMBL28585559 | 0.82 | TAAR1 (0.61) | TAAR1GAASMN1; SMN2HTR1AHTT | |
| SCHEMBL22360002 | 0.82 | CYP4F2 (0.53) | TAAR1SMN1; SMN2HTR1ARAB9ACA2 | |
| SCHEMBL31414967 | 0.82 | TAAR1 (0.75) | TAAR1GAASMN1; SMN2HTR1AKDM4E | |
| Hydrochloric Acid SCHEMBL10671793 | 0.82 | TAAR1 (0.49) | TAAR1GAASMN1; SMN2HTTKDM4E | |
| SCHEMBL7447359 | 0.81 | PARP1 (0.49) | TAAR1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL9853948 | 0.80 | TAAR1 (0.62) | TAAR1GAASMN1; SMN2HTR1AHTT | |
| SCHEMBL4062296 | 0.78 | TTR (0.45) | TAAR1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL3749613 | 0.78 | TAAR1 (0.64) | TAAR1GAASMN1; SMN2HTR1AKDM4E | |
| SCHEMBL10997900 | 0.78 | TAAR1 (0.64) | TAAR1GAASMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020167952-A1 | MAT2A INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-08-20 | — | — | WO | disclosed |
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |