Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098501 | 0.74 | SLC13A5 (0.50) | SLC13A5KEAP1GRM2GRM3NPC1 | |
| SCHEMBL15707943 | 0.74 | SLC13A5 (0.50) | SLC13A5KEAP1GRM2GRM3NPC1 | |
| SCHEMBL8504022 | 0.73 | ALDH1A1 (0.40) | KMT2AMEN1HTTL3MBTL1SLC13A5 | |
| SCHEMBL5475208 | 0.72 | ALDH1A1 (0.50) | KMT2AMEN1HTTL3MBTL1SLC13A5 | |
| SCHEMBL6628038 | 0.72 | ALDH1A1 (0.50) | KMT2AMEN1HTTL3MBTL1SLC13A5 | |
| SCHEMBL6632235 | 0.72 | ALDH1A1 (0.50) | KMT2AMEN1HTTL3MBTL1SLC13A5 | |
| SCHEMBL1856371 | 0.71 | KEAP1 (0.52) | SLC13A5KEAP1GRM2GRM3NPC1 | |
| SCHEMBL5903600 | 0.71 | ALDH1A1 (0.43) | KMT2AMEN1HTTL3MBTL1ALOX5 | |
| SCHEMBL8773724 | 0.71 | ALDH1A1 (0.43) | KMT2AMEN1HTTL3MBTL1ALOX5 | |
| SCHEMBL7441576 | 0.71 | GRM2 (0.53) | SLC13A5KEAP1GRM2GRM3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |