SCHEMBL741769

SCHEMBL741769

Nc1ccc(-c2ccc(-c3ccc(N)c(-c4ccc5ccccc5c4)c3-c3ccc4ccccc4c3)c(-c3ccc4ccccc4c3)c2)c(-c2ccc3ccccc3c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
CYP3A4 P08684 2/20 0.44
HSD17B10 Q99714 2/20 0.44
GSTP1 P09211 1/20 0.40
HIF1A Q16665 2/20 0.40
ALOX15 P16050 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
HBB P68871 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
DHFR P00374 1/20 0.39
KDM4E B2RXH2 2/20 0.38
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
IKBKB O14920 1/20 0.38
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
CYP1A2 P05177 2/20 0.36
PTPRC P08575 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259164 0.86 GSTP1 (0.47) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A
SCHEMBL28127187 0.83 ALDH1A1 (0.47) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A
SCHEMBL4450641 0.82 CYP1A1 (0.47) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A
SCHEMBL7040121 0.81 ALDH1A1 (0.57) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A
SCHEMBL30422833 0.81 ALDH1A1 (0.57) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A
SCHEMBL24296053 0.80 ALDH1A1 (0.55) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A
SCHEMBL31183073 0.80 ALDH1A1 (0.55) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A
SCHEMBL25486686 0.80 ALDH1A1 (0.55) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A
SCHEMBL24079285 0.80 ALDH1A1 (0.55) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A
SCHEMBL27557165 0.80 CYP3A4 (0.55) ALDH1A1CYP3A4HSD17B10GSTP1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2430677-A1 INTERNAL CONNECTOR FOR ORGANIC ELECTRONIC DEVICES Global OLED Technology LLC (US) 2012-03-21 EP disclosed
WO-2010132236-A1 INTERNAL CONNECTOR FOR ORGANIC ELECTRONIC DEVICES GLOBAL OLED TECHNOLOGY LLC. (US) 2010-11-18 WO disclosed
EP-1920481-A1 ELECTROLUMINESCENT DEVICE WITH RED TRIPLET EMITTER EASTMAN KODAK COMPANY (US) 2008-05-14 EP disclosed
EP-1851801-A1 TANDEM OLED HAVING AN ORGANIC INTERMEDIATE CONNECTOR EASTMAN KODAK COMPANY (US) 2007-11-07 EP disclosed
WO-2007027433-A1 ELECTROLUMINESCENT DEVICE WITH RED TRIPLET EMITTER EASTMAN KODAK COMPANY (US) 2007-03-08 WO disclosed
WO-2006091560-A1 TANDEM OLED HAVING AN ORGANIC INTERMEDIATE CONNECTOR EASTMAN KODAK COMPANY (US) 2006-08-31 WO disclosed
WO-2005109543-A2 OLED DEVICE USING REDUCED DRIVE VOLTAGE EASTMAN KODAK COMPANY (US) 2005-11-17 WO disclosed