Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259164 | 0.95 | GSTP1 (0.47) | CYP1A1CYP1B1ADORA2AADORA1HSD17B1 | |
| SCHEMBL35312 | 0.87 | CYP1A2 (0.52) | CYP1A1CYP1B1ADORA2AADORA1HSD17B1 | |
| SCHEMBL28127187 | 0.85 | ALDH1A1 (0.47) | CYP1A1CYP1B1ADORA2AADORA1GSTP1 | |
| SCHEMBL1720546 | 0.83 | HSD17B10 (0.48) | ADORA2AIKBKBCYP1A2KDM4EALDH1A1 | |
| SCHEMBL297637 | 0.83 | ALDH1A1 (0.48) | ADORA2AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28235937 | 0.82 | ESR1 (0.38) | CYP1A1CYP1B1ADORA2AADORA1HSD17B1 | |
| SCHEMBL4002627 | 0.82 | GSTP1 (0.53) | CYP1A1CYP1B1ADORA2AADORA1HSD17B1 | |
| SCHEMBL741769 | 0.82 | ALDH1A1 (0.44) | CYP1A1CYP1B1ADORA2AADORA1HSD17B1 | |
| SCHEMBL1901543 | 0.81 | GSTP1 (0.48) | CYP1A1CYP1B1ADORA2AADORA1HSD17B1 | |
| Naphthalene SCHEMBL3868843 | 0.81 | HSD17B10 (0.48) | CYP1A1CYP1B1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598010-B2 | Triarylamine dimer derivative having amorphous phase | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-20050154234-A1 | Triarylamine dimer derivative having amorphous phase | ORIENT CHEMICAL IND., LTD. (JP) | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154234-A1 | Triarylamine dimer derivative having amorphous phase | NAT1, AHR, ARNT | CYP1A1 73/4885CYP1B1 117/4885ADORA2A 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.