Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 5/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384058 | 1.00 | PSMB1 (0.60) | PSMB1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7412449 | 0.91 | PSMB1 (0.61) | PSMB1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7420596 | 0.91 | PSMB1 (0.61) | PSMB1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7418250 | 0.91 | PSMB1 (0.61) | PSMB1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7270223 | 0.91 | PSMB1 (0.59) | PSMB1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5344617 | 0.88 | ADORA3 (0.59) | PSMB1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7279478 | 0.87 | ADORA3 (0.56) | PSMB1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL27327218 | 0.87 | PSMB1 (0.56) | PSMB1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL10803689 | 0.86 | MME (0.63) | CTSLMMEECE1TACR1CTSB | |
| SCHEMBL10803697 | 0.86 | MME (0.63) | CTSLMMEECE1TACR1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |