Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 8/20 | 0.37 |
| ▸ | FPR1 | P21462 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417832 | 1.00 | ITGB3 (0.57) | ITGB3ITGA2BF2FPR2FPR1 | |
| SCHEMBL8108543 | 0.89 | ITGB3 (0.71) | ITGB3ITGA2BF2FPR2FPR1 | |
| SCHEMBL8115160 | 0.89 | ITGB3 (0.71) | ITGB3ITGA2BF2FPR2FPR1 | |
| SCHEMBL7419223 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BF2FPR2FPR1 | |
| Acetic Acid SCHEMBL7414160 | 0.87 | ITGB3 (0.68) | ITGB3ITGA2BF2FPR2FPR1 | |
| SCHEMBL7530926 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7412598 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7419456 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7419451 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7412595 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796245-B1 | PROCESS FOR THE PREPARATION OF AMIDINO PHENYL PYRROLIDINE BETA-ALANINE UREA ANALOGS | SEARLE & CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5659063-A | AMINE-BLOCKED METHIONINE ANALOG CYCLIZABLE TO A LACTAM IN NONVOLATILE OR NONTOXIC REAGENTS; ANTITHROMBOTIC AGENTS | G. D. SEARLE & CO. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5610296-A | CHEMICAL INTERMEDIATES OF ANTITHROMBOTICS | G. D. SEARLE & CO. (US) | 1997-03-11 | — | — | US | disclosed |
| US-5576447-A | Process for the preparation of amidino phenyl pyrrolidine β-alanine urea analogs | G. D. SEARLE & CO. (US) | 1996-11-19 | — | — | US | disclosed |
| US-5484946-A | CYCLIZATION AND DEHYDRATION A METHIONINE DERIVATIVE | G. D. SEARLE & CO. (US) | 1996-01-16 | — | — | US | disclosed |