Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743603 | 0.87 | KMT2A (0.41) | TSHRKMT2AL3MBTL1SYKCPB1 | |
| SCHEMBL741638 | 0.83 | KMT2A (0.47) | TSHRKMT2AL3MBTL1SYKCPB1 | |
| SCHEMBL713910 | 0.77 | CPB1 (0.50) | CYP3A4TSHRKMT2AL3MBTL1RAB9A | |
| SCHEMBL715263 | 0.77 | CPB1 (0.50) | CYP3A4TSHRKMT2AL3MBTL1RAB9A | |
| SCHEMBL714916 | 0.77 | CPB1 (0.50) | CYP3A4TSHRKMT2AL3MBTL1RAB9A | |
| SCHEMBL715729 | 0.77 | CPB1 (0.50) | CYP3A4TSHRKMT2AL3MBTL1RAB9A | |
| SCHEMBL714915 | 0.77 | CPB1 (0.50) | CYP3A4TSHRKMT2AL3MBTL1RAB9A | |
| SCHEMBL717307 | 0.77 | CPB1 (0.50) | CYP3A4TSHRKMT2AL3MBTL1RAB9A | |
| SCHEMBL4089080 | 0.77 | CPB1 (0.50) | CYP3A4TSHRKMT2AL3MBTL1RAB9A | |
| SCHEMBL713911 | 0.77 | CPB1 (0.50) | CYP3A4TSHRKMT2AL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |