Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743603 | 0.83 | KMT2A (0.41) | KMT2AL3MBTL1PDE4BCTSLSYK | |
| SCHEMBL741822 | 0.83 | CYP3A4 (0.41) | KMT2AL3MBTL1PDE4BCTSLSYK | |
| SCHEMBL30440711 | 0.80 | KMT2A (0.51) | KMT2AL3MBTL1CTSLSYKALDH1A1 | |
| SCHEMBL14169795 | 0.78 | KMT2A (0.49) | KMT2AL3MBTL1PDE4BCTSLSYK | |
| SCHEMBL4033681 | 0.78 | CPB1 (0.54) | KMT2AL3MBTL1PDE4BCTSLSYK | |
| SCHEMBL23460765 | 0.78 | KMT2A (0.51) | KMT2AL3MBTL1CTSLSYKALDH1A1 | |
| SCHEMBL4823158 | 0.77 | CTSS (0.54) | KMT2AL3MBTL1CTSLSYK | |
| SCHEMBL10137650 | 0.76 | CPB1 (0.56) | KMT2AL3MBTL1PDE4BCTSLSYK | |
| SCHEMBL12873056 | 0.76 | CPB1 (0.56) | KMT2AL3MBTL1PDE4BCTSLSYK | |
| SCHEMBL8657174 | 0.76 | KMT2A (0.43) | KMT2AL3MBTL1PDE4BCTSLSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |