Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.67 |
| ▸ | HTR1A | P08908 | 2/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 2/20 | 0.67 |
| ▸ | HTR6 | P50406 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | HTR2C | P28335 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865544 | 0.88 | DRD2 (0.59) | DRD2HTR1ASLC6A4HTR7HTR6 | |
| SCHEMBL4867310 | 0.85 | HTR1A (0.62) | DRD2HTR1ASLC6A4HTR6HTR2A | |
| SCHEMBL4872356 | 0.85 | DRD2 (0.58) | DRD2HTR1ASLC6A4HTR7HTR6 | |
| SCHEMBL4862051 | 0.82 | DRD2 (0.59) | DRD2HTR1ASLC6A4HTR7HTR6 | |
| SCHEMBL4869010 | 0.81 | HTR1A (0.55) | DRD2HTR1ASLC6A4HTR7HTR6 | |
| SCHEMBL1040205 | 0.81 | DRD2 (1.00) | DRD2HTR1ASLC6A4HTR7HTR6 | |
| SCHEMBL4873344 | 0.80 | DRD2 (0.56) | DRD2HTR1ASLC6A4HTR2A | |
| SCHEMBL793141 | 0.79 | DRD2 (1.00) | DRD2HTR1ASLC6A4HTR7HTR6 | |
| SCHEMBL4872140 | 0.79 | DRD2 (0.54) | DRD2HTR1ASLC6A4HTR2A | |
| SCHEMBL790948 | 0.78 | DRD2 (0.72) | DRD2HTR1ASLC6A4HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200072-A2 | METHOD OF TREATING PSYCHOTIC DISORDERS | Solvay Pharmaceuticals B.V. (NL) | 2002-05-02 | — | — | EP | disclosed |
| WO-2000069424-A2 | METHOD OF TREATING PSYCHOTIC DISORDERS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2000-11-23 | — | — | WO | disclosed |