SCHEMBL7418328

SCHEMBL7418328

Cc1csc(C)c1C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15691391 0.78
SCHEMBL15691410 0.78 TSHR (0.34)
SCHEMBL7990423 0.76
SCHEMBL7469857 0.76
SCHEMBL1820046 0.76
SCHEMBL15691387 0.76
SCHEMBL11948739 0.69 ALDH1A1 (0.49)
SCHEMBL10713413 0.69 KDM4E (0.31)
SCHEMBL29211178 0.69 ALDH1A1 (0.54)
SCHEMBL31531435 0.68 MAPT (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110045974-A1 Substituted Triazinylmethyl Sulfonamides BASF SE (DE) 2011-02-24 US disclosed
EP-1169338-A2 LOW-MOLECULAR INHIBITORS OF COMPLEMENT PROTEASES BASF AKTIENGESELLSCHAFT (DE) 2002-01-09 EP disclosed
EP-1165601-A2 PRODRUGS OF THROMBIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 2002-01-02 EP disclosed
EP-1051431-A1 THROMBIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 2000-11-15 EP disclosed
WO-2000061609-A2 PRODRUGS OF THROMBIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 2000-10-19 WO disclosed
WO-2000061608-A2 LOW-MOLECULAR INHIBITORS OF COMPLEMENT PROTEASES BASF AKTIENGESELLSCHAFT (DE) 2000-10-19 WO disclosed
WO-1999037668-A1 THROMBIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1999-07-29 WO disclosed