Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25171910 | 0.70 | ALDH1A1 (1.00) | ALDH1A1HTTHPGDNPSR1TP53 | |
| SCHEMBL7418328 | 0.69 | — | — | |
| SCHEMBL1820046 | 0.66 | — | — | |
| SCHEMBL7990423 | 0.66 | — | — | |
| SCHEMBL24553595 | 0.63 | ALDH1A1 (0.50) | ALDH1A1HTTHPGDNPSR1TP53 | |
| SCHEMBL24552932 | 0.62 | ALDH1A1 (0.45) | ALDH1A1HTTHPGDNPSR1TP53 | |
| SCHEMBL24553821 | 0.62 | ALDH1A1 (0.49) | ALDH1A1HTTHPGDNPSR1TP53 | |
| SCHEMBL24553691 | 0.61 | ALDH1A1 (0.47) | ALDH1A1HTTHPGDNPSR1TP53 | |
| SCHEMBL24553663 | 0.61 | ALDH1A1 (0.47) | ALDH1A1HTTHPGDNPSR1TP53 | |
| SCHEMBL23245729 | 0.60 | TRPV4 (0.45) | ALDH1A1HTTHPGDNPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538078-B | Polycyclic compound for inhibiting DHX33 helicase | 成都开悦生命科技有限公司 | 2024-03-19 | — | — | CN | disclosed |