Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.80 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.80 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095786 | 0.94 | ITGB3 (0.71) | ITGB3ITGA2BFPR2FPR1PRSS1 | |
| SCHEMBL7451885 | 0.91 | ITGB3 (0.84) | ITGB3ITGA2BFPR2FPR1 | |
| Hydrochloric Acid SCHEMBL7451874 | 0.90 | ITGB3 (0.82) | ITGB3ITGA2BFPR2FPR1 | |
| Orbofiban SCHEMBL7854981 | 0.89 | ITGB3 (1.00) | ITGB3ITGA2BFPR2FPR1PRSS1 | |
| Orbofiban SCHEMBL7415135 | 0.89 | ITGB3 (1.00) | ITGB3ITGA2BFPR2FPR1PRSS1 | |
| Orbofiban SCHEMBL7417473 | 0.88 | ITGB3 (0.95) | ITGB3ITGA2BFPR2FPR1PRSS1 | |
| SCHEMBL7411805 | 0.88 | ITGB3 (0.73) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7448817 | 0.88 | ITGB3 (0.73) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7448793 | 0.88 | ITGB3 (0.78) | ITGB3ITGA2BFPR2FPR1PRSS1 | |
| Acetic Acid SCHEMBL7418342 | 0.87 | ITGB3 (0.75) | ITGB3ITGA2BFPR2FPR1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484946-A | CYCLIZATION AND DEHYDRATION A METHIONINE DERIVATIVE | G. D. SEARLE & CO. (US) | 1996-01-16 | — | — | US | disclosed |