Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | BHMT | Q93088 | 3/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876560 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1KIF11SLC7A5 | |
| SCHEMBL7184921 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1KIF11SLC7A5 | |
| SCHEMBL12438551 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1KIF11SLC7A5 | |
| SCHEMBL6501684 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1KIF11SLC7A5 | |
| SCHEMBL6234510 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1KIF11SLC7A5 | |
| SCHEMBL2875767 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1KIF11SLC7A5 | |
| SCHEMBL6555262 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1KIF11SLC7A5 | |
| SCHEMBL19371196 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTPTGS1KIF11SLC7A5 | |
| SCHEMBL14066341 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL8340854 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |
| EP-1009737-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999006340-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0632052-B1 | Endothelin antagonistic peptides | BANYU PHARMA CO LTD (JP) | 1998-09-30 | — | — | EP | disclosed |