Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066341 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL7184921 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL7418366 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL7876560 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL6670760 | 0.75 | DPP4 (0.32) | ALDH1A1MAPTPTGS1DPP4 | |
| SCHEMBL17435745 | 0.75 | SMN1; SMN2 (0.34) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL7346068 | 0.75 | SMN1; SMN2 (0.34) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL17435743 | 0.75 | SMN1; SMN2 (0.34) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL2032829 | 0.73 | — | — | |
| SCHEMBL738238 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| US-5714491-A | ANTICANCER AND ANTITUMOR AGENT | CELLTECH THERAPEUTICS LIMITED (GB) | 1998-02-03 | — | — | US | disclosed |