Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18822177 | 0.82 | MAPT (0.47) | MAPTRAB9ACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL19125730 | 0.81 | MAPT (0.45) | MAPTRAB9ACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL4766309 | 0.80 | SMN1; SMN2 (0.62) | MAPTRAB9ACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL19111159 | 0.80 | MAPT (0.44) | MAPTRAB9ACYP3A4TSHRLMNA | |
| SCHEMBL6790694 | 0.78 | L3MBTL1 (0.46) | MAPTRAB9ASMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL19578990 | 0.78 | KMT2A (0.58) | MAPTRAB9ATSHRSMN1; SMN2KMT2A | |
| SCHEMBL205765 | 0.78 | MGLL (0.65) | MAPTRAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22388846 | 0.78 | KMT2A (0.76) | MAPTRAB9ATSHRSMN1; SMN2KMT2A | |
| SCHEMBL4816347 | 0.76 | PTPN11 (0.64) | MAPTRAB9AKMT2AMEN1PTPN11 | |
| SCHEMBL8456195 | 0.76 | SMN1; SMN2 (0.70) | MAPTRAB9ACYP3A4TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996032379-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-17 | — | — | WO | disclosed |