Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 3/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 4/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29504613 | 0.81 | LIPG (0.50) | LIPGLIPEENPP2ORAI1ORAI2 | |
| SCHEMBL520432 | 0.81 | LIPG (0.50) | LIPGLIPEENPP2ORAI1ORAI2 | |
| SCHEMBL12544470 | 0.78 | LIPG (0.52) | LIPGLIPEENPP2ORAI1ORAI2 | |
| SCHEMBL29952834 | 0.78 | LIPG (0.52) | LIPGLIPEENPP2ORAI1ORAI2 | |
| SCHEMBL29952337 | 0.77 | IDO1 (0.48) | LIPGLIPEENPP2IDO1 | |
| SCHEMBL31071990 | 0.76 | LIPG (0.46) | LIPGLIPEENPP2ORAI1ORAI2 | |
| SCHEMBL21767575 | 0.76 | LIPG (0.46) | LIPGLIPEENPP2ORAI1ORAI2 | |
| SCHEMBL29408426 | 0.76 | LIPG (0.46) | LIPGLIPEENPP2ORAI1ORAI2 | |
| SCHEMBL1260133 | 0.76 | LIPG (0.50) | LIPGLIPE | |
| SCHEMBL1773603 | 0.76 | LIPG (0.46) | LIPGLIPEENPP2ORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206449-A1 | LACTAM INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-1196436-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001007407-A1 | LACTAM INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2001002424-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | DU PONT PHARMACEUTICALS COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |