Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774965 | 0.82 | IDO1 (0.67) | IDO1MAOAMAOBNR4A2PNMT | |
| SCHEMBL29952834 | 0.79 | LIPG (0.52) | IDO1LIPGKDM4ETDP1ENPP2 | |
| SCHEMBL12544470 | 0.79 | LIPG (0.52) | IDO1LIPGKDM4ETDP1ENPP2 | |
| SCHEMBL2552633 | 0.79 | FABP4 (0.44) | IDO1LIPGMAOAMAOBNR4A2 | |
| SCHEMBL2561187 | 0.79 | TP53 (0.56) | KDM4EENPP2HPGDALDH1A1GAA | |
| SCHEMBL2554369 | 0.79 | LIPE (0.60) | IDO1MAOAMAOBKDM4ETDP1 | |
| SCHEMBL30905963 | 0.79 | LIPE (0.60) | IDO1MAOAMAOBKDM4ETDP1 | |
| SCHEMBL29955081 | 0.78 | IDO1 (0.44) | IDO1LIPGMAOAMAOBKDM4E | |
| SCHEMBL7418607 | 0.77 | LIPG (0.48) | IDO1LIPGENPP2LIPE | |
| SCHEMBL595045 | 0.76 | LIPG (0.44) | IDO1LIPGENPP2LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |