Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 6/20 | 0.42 |
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 5/20 | 0.41 |
| ▸ | HTR6 | P50406 | 6/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8558141 | 0.99 | MCHR1 (0.43) | MCHR1F10F2ACHEKHK | |
| SCHEMBL7473162 | 0.90 | F10 (0.43) | MCHR1F10F2KHKPRSS1 | |
| Hydrochloric Acid SCHEMBL7422325 | 0.89 | F10 (0.43) | MCHR1F10F2ACHEKHK | |
| Hydrochloric Acid SCHEMBL8561724 | 0.89 | F10 (0.43) | MCHR1F10F2KHKPRSS1 | |
| SCHEMBL7471852 | 0.86 | ACHE (0.46) | MCHR1F10F2ACHEKHK | |
| SCHEMBL7471860 | 0.86 | ACHE (0.46) | MCHR1F10F2ACHEKHK | |
| Hydrochloric Acid SCHEMBL8558247 | 0.85 | ACHE (0.46) | MCHR1F10F2ACHEKHK | |
| Hydrochloric Acid SCHEMBL7471534 | 0.83 | F2 (0.42) | MCHR1F10F2ACHEKHK | |
| Hydrochloric Acid SCHEMBL7470901 | 0.82 | F10 (0.39) | F10F2ACHEPRSS1 | |
| Hydrochloric Acid SCHEMBL8560707 | 0.82 | ACHE (0.43) | MCHR1F10F2ACHEKHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | claimed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | claimed |
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |