Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.43 |
| ▸ | F2 | P00734 | 6/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | HPN | P05981 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8561724 | 0.99 | F10 (0.43) | F10F2PRSS1MCHR1KHK | |
| SCHEMBL7418636 | 0.90 | MCHR1 (0.44) | F10F2PRSS1MCHR1KHK | |
| SCHEMBL7477055 | 0.89 | SMN1; SMN2 (0.40) | F10F2PRSS1MCHR1KHK | |
| Hydrochloric Acid SCHEMBL8558141 | 0.89 | MCHR1 (0.43) | F10F2PRSS1MCHR1KHK | |
| SCHEMBL8562349 | 0.87 | F2 (0.39) | F10F2KHKS1PR1CYP17A1 | |
| SCHEMBL8562341 | 0.87 | F2 (0.39) | F10F2KHKS1PR1CYP17A1 | |
| Hydrochloric Acid SCHEMBL7470901 | 0.86 | F10 (0.39) | F10F2PRSS1S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL8560749 | 0.86 | F2 (0.38) | F10F2PRSS1KHKCYP17A1 | |
| Hydrochloric Acid SCHEMBL8566388 | 0.83 | F10 (0.36) | F10F2PRSS1KHK | |
| Hydrochloric Acid SCHEMBL8597445 | 0.82 | ACHE (0.37) | F10F2PRSS1KHKCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | claimed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | claimed |
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |