Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.47 |
| ▸ | FNTB | P49356 | 17/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 15/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425782 | 0.87 | FNTA (0.49) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7418974 | 0.84 | RIPK1 (0.41) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7424679 | 0.80 | FNTA (0.59) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7420645 | 0.78 | FNTA (0.49) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7420186 | 0.76 | FNTA (0.55) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7428975 | 0.76 | FNTA (0.53) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7417103 | 0.76 | FNTA (0.57) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7423011 | 0.76 | FNTA (0.53) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7419872 | 0.76 | FNTA (0.51) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7418605 | 0.76 | FNTA (0.53) | FNTAFNTBPGGT1BKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |