Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 7/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425776 | 0.87 | CCR3 (0.45) | RIPK1BRD4HSD11B1GPR6 | |
| SCHEMBL7418976 | 0.84 | FNTA (0.47) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7424674 | 0.79 | HDAC1 (0.52) | BRD4FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL2332156 | 0.78 | FNTA (0.46) | RIPK1BRD4FNTAFNTBPGGT1B | |
| SCHEMBL7420641 | 0.78 | BRD4 (0.43) | RIPK1BRD4FNTAFNTBPGGT1B | |
| SCHEMBL7423007 | 0.77 | GRM5 (0.52) | RIPK1FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7420184 | 0.77 | SRC (0.49) | RIPK1BRD4FNTAFNTBPGGT1B | |
| SCHEMBL7417098 | 0.77 | ROCK2 (0.47) | RIPK1BRD4FNTAFNTBPGGT1B | |
| SCHEMBL7419869 | 0.76 | MCHR1 (0.49) | BRD4 | |
| SCHEMBL7418602 | 0.76 | SRC (0.48) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |