Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8401964 | 0.95 | CHRM2 (0.44) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7419072 | 0.83 | CHRM2 (0.46) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8406643 | 0.81 | CHRM2 (0.44) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8404872 | 0.80 | CHRM1 (0.41) | CHRM1HTR2ACHRNB2CHRNA4CHRM2 | |
| Oxalic Acid SCHEMBL7424487 | 0.79 | CHRM2 (0.52) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8406017 | 0.79 | CHRM2 (0.46) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8405398 | 0.79 | CHRM2 (0.43) | CHRM1HTR2ACHRNB2CHRNA4CHRM2 | |
| SCHEMBL8402127 | 0.78 | CHRM1 (0.46) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| Oxalic Acid SCHEMBL7477838 | 0.77 | CHRM2 (0.50) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8404876 | 0.77 | CHRM1 (0.39) | CHRM1HTR2ACHRNB2CHRNA4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994373-A | COGNITION ACTIVATORS; GASTROINTESTINAL DISORDERS; PSYCHOLOGICAL DISORDERS | NOVO NORDISK A/S NOVO ALLE DK 2880 (DK) | 1999-11-30 | — | — | US | claimed |