Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.62 |
| ▸ | F2 | P00734 | 2/20 | 0.62 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.62 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.62 |
| ▸ | PLAU | P00749 | 1/20 | 0.62 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.62 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.62 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.62 |
| ▸ | F10 | P00742 | 1/20 | 0.62 |
| ▸ | PLG | P00747 | 1/20 | 0.62 |
| ▸ | S100B | P04271 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | AOC1 | P19801 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427347 | 0.99 | PRMT1 (0.65) | PRSS1PRMT1F2ST14TMPRSS2 | |
| SCHEMBL7989663 | 0.99 | PRMT1 (0.65) | PRSS1PRMT1F2ST14TMPRSS2 | |
| SCHEMBL7986829 | 0.99 | PRMT1 (0.65) | PRSS1PRMT1F2ST14TMPRSS2 | |
| SCHEMBL7982578 | 0.97 | TMPRSS2 (0.64) | PRSS1PRMT1F2ST14TMPRSS2 | |
| SCHEMBL7986010 | 0.96 | PRSS1 (0.63) | PRSS1PRMT1F2ST14TMPRSS2 | |
| SCHEMBL7972474 | 0.92 | TMPRSS2 (0.57) | PRSS1PRMT1F2ST14TMPRSS2 | |
| SCHEMBL7972008 | 0.89 | F10 (0.62) | PRSS1F2TMPRSS2F10PLG | |
| SCHEMBL7392566 | 0.87 | F10 (0.56) | PRSS1F2F10PLGDRD3 | |
| SCHEMBL7425136 | 0.86 | PRSS1 (0.57) | PRSS1PRMT1F2ST14PLAU | |
| SCHEMBL7989809 | 0.86 | PRSS1 (0.57) | PRSS1PRMT1F2ST14PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |
| WO-1999024395-A1 | COMPOUNDS WHICH INHIBIT TRYPTASE ACTIVITY | ARRAY BIOPHARMA, INC. (US) | 1999-05-20 | — | — | WO | disclosed |