Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.39 |
| ▸ | NPY1R | P25929 | 6/20 | 0.39 |
| ▸ | NPY2R | P49146 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | OTC | P00480 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 2/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419967 | 1.00 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL2183420 | 0.90 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL1521188 | 0.90 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL1521191 | 0.90 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL11597903 | 0.89 | FNTA (0.36) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL2183995 | 0.89 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL9225106 | 0.88 | NPY4R (0.40) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL9225097 | 0.88 | NPY4R (0.40) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL8697740 | 0.84 | GNAI3 (0.46) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL2182733 | 0.84 | DPP7 (0.51) | NPY4RNPY1RNPY2RNPY5RDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431113-A4 | ATRIAL PEPTIDE DERIVATIVES | — | 1992-01-22 | — | — | EP | disclosed |
| EP-0431113-A1 | ATRIAL PEPTIDE DERIVATIVES | ABBOTT LABORATORIES (US) | 1991-06-12 | — | — | EP | disclosed |
| WO-1990014362-A1 | ATRIAL PEPTIDE DERIVATIVES | ABBOTT LABORATORIES (US) | 1990-11-29 | — | — | WO | disclosed |