Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 12/20 | 0.46 |
| ▸ | NPY1R | P25929 | 7/20 | 0.46 |
| ▸ | NPY2R | P49146 | 5/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 2/20 | 0.35 |
| ▸ | NMT1 | P30419 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807371 | 0.89 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL10943635 | 0.89 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL7419957 | 0.89 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL7419967 | 0.89 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL9807377 | 0.88 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL15263460 | 0.87 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL2195938 | 0.86 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL4586183 | 0.86 | GNAI3 (0.46) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL8697740 | 0.86 | GNAI3 (0.46) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL5578552 | 0.86 | GNAI3 (0.46) | NPY4RNPY1RNPY2RNPY5RGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | NPY4R 567/4885NPY1R 544/4885NPY2R 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.