Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 6/20 | 0.44 |
| ▸ | CTSL | P07711 | 6/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSH | P09668 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25716962 | 0.82 | KLK7 (0.51) | MEN1KMT2ANPSR1CTSLCTSS | |
| SCHEMBL5031605 | 0.82 | KLK7 (0.51) | MEN1KMT2ANPSR1CTSLCTSS | |
| SCHEMBL30461760 | 0.80 | KMT2A (0.53) | MEN1KMT2ANPSR1CTSSFKBP1A | |
| SCHEMBL3127052 | 0.80 | TACR1 (0.51) | CTSKCTSLCTSBCTSSITGB3 | |
| SCHEMBL30461742 | 0.77 | MEN1 (0.54) | MEN1KMT2ANPSR1CTSSFKBP1A | |
| SCHEMBL29400872 | 0.77 | ITGB3 (0.58) | MEN1KMT2ANPSR1FKBP1AITGB3 | |
| SCHEMBL30461745 | 0.77 | MEN1 (0.56) | MEN1KMT2ANPSR1CTSSFKBP1A | |
| SCHEMBL30461756 | 0.77 | MEN1 (0.56) | MEN1KMT2ANPSR1CTSSFKBP1A | |
| SCHEMBL30461732 | 0.76 | MEN1 (0.47) | MEN1KMT2ANPSR1CTSKCTSL | |
| SCHEMBL30461750 | 0.76 | MEN1 (0.47) | MEN1KMT2ANPSR1CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053226-A1 | SULFONYLAMINO DERIVATIVES WHICH INHIBIT MATRIX-DEGRADING METALLOPROTEINASES | Novartis AG (CH) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999042443-A1 | SULFONYLAMINO DERIVATIVES WHICH INHIBIT MATRIX-DEGRADING METALLOPROTEINASES | NOVARTIS AG (CH) | 1999-08-26 | — | — | WO | disclosed |