SCHEMBL7420070

SCHEMBL7420070

CC1(F)C=CC(C(=O)c2ccccc2)=CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SRD5A2 P31213 1/20 0.35
HPGD P15428 3/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
HPGDS O60760 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
MAPK1 P28482 1/20 0.34
EZH2 Q15910 1/20 0.34
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34
ELANE P08246 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
AKR1C3 P42330 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL993046 0.85 ALDH1A1 (0.43) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL2470211 0.84 ALDH1A1 (0.42) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL8574305 0.84 ALDH1A1 (0.36) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL4959091 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL19179591 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL5677233 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL7430914 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL26630609 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL7423422 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27620599 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891585-A Preparation method of soluble polyaryletherketone film with low toxicity solvent 大连中科聚合新材料科技有限公司 2023-10-17 CN claimed
CN-116515100-A Phenolphthalein-based polyaryletherketone polymer and end capping method 浙江帕尔科新材料有限公司 2023-08-01 CN claimed
CN-105967985-A Preparation method of 4-methyl-4'-fluorine-diphenyl ketone 上海应用技术学院 2016-09-28 CN claimed
CN-116891585-A Preparation method of soluble polyaryletherketone film with low toxicity solvent 大连中科聚合新材料科技有限公司 2023-10-17 CN disclosed
CN-116515100-A Phenolphthalein-based polyaryletherketone polymer and end capping method 浙江帕尔科新材料有限公司 2023-08-01 CN disclosed
CN-105967985-A Preparation method of 4-methyl-4'-fluorine-diphenyl ketone 上海应用技术学院 2016-09-28 CN disclosed
EP-0958280-A1 ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME SUNTORY LIMITED (JP) 1999-11-24 EP disclosed
WO-1999023072-A1 ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME SUNTORY LIMITED (JP) 1999-05-14 WO disclosed