SCHEMBL8574305

SCHEMBL8574305

COC1(F)C=CC(C(=O)c2ccccc2)=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.35
HPGD P15428 5/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ELANE P08246 2/20 0.34
PTGS1 P23219 2/20 0.34
PTGS2 P35354 2/20 0.34
MAPT P10636 4/20 0.33
KDM4E B2RXH2 3/20 0.33
HSD17B10 Q99714 3/20 0.33
ALOX15 P16050 2/20 0.33
MAPK1 P28482 2/20 0.33
LMNA P02545 3/20 0.33
CYP3A4 P08684 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3643054 0.84 ALDH1A1 (0.37) ALDH1A1TSHRHPGDNPC1RAB9A
SCHEMBL27427467 0.84 KMT2A (0.33) ALDH1A1HPGDELANEPTGS1PTGS2
SCHEMBL7420070 0.84 ALDH1A1 (0.39) ALDH1A1HPGDNPC1RAB9AELANE
SCHEMBL210845 0.82 ALDH1A1 (0.38) ALDH1A1TSHRHPGDNPC1RAB9A
SCHEMBL993046 0.82 ALDH1A1 (0.43) ALDH1A1TSHRHPGDNPC1RAB9A
SCHEMBL27903354 0.81 ALDH1A1 (0.37) ALDH1A1TSHRHPGDNPC1RAB9A
SCHEMBL30148113 0.80 MEN1 (0.38) ALDH1A1HPGDNPC1RAB9AELANE
SCHEMBL3041974 0.80 ALDH1A1 (0.36) ALDH1A1TSHRHPGDNPC1RAB9A
SCHEMBL27506088 0.80 ALDH1A1 (0.36) ALDH1A1TSHRHPGDNPC1RAB9A
SCHEMBL19179591 0.79 ALDH1A1 (0.41) ALDH1A1TSHRHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891585-A Preparation method of soluble polyaryletherketone film with low toxicity solvent 大连中科聚合新材料科技有限公司 2023-10-17 CN claimed
CN-100372877-C High molecular type diphenyl ketone light initiator and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2008-03-05 CN claimed
CN-100372875-C High molecular benzophenone photoinitiator and its prepn process UNIV SHANGHAI JIAOTONG (CN) 2008-03-05 CN claimed
CN-1858078-A High molecular type diphenyl ketone light initiator and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-11-08 CN claimed
CN-1847275-A High molecular benzophenone photoinitiator and its prepn process UNIV SHANGHAI JIAOTONG (CN) 2006-10-18 CN claimed
CN-1789245-A Sulfur-containing, polymerizable benzophenone photoinitiator and preparation method thereof UNIV SHANGHAI JIAOTONG (CN) 2006-06-21 CN claimed
CN-1727335-A Photoinitiator of benzophenone containing N-phenyl maleimide base group, and preparation method UNIV SHANGHAI JIAOTONG (CN) 2006-02-01 CN claimed
CN-116891585-A Preparation method of soluble polyaryletherketone film with low toxicity solvent 大连中科聚合新材料科技有限公司 2023-10-17 CN disclosed
CN-114230785-B Radiation-resistant polyether-ether-ketone polymer and preparation method thereof 吉林省中研高分子材料股份有限公司 2023-03-03 CN disclosed
CN-114230785-A Radiation-resistant polyether-ether-ketone polymer and preparation method thereof 吉林省中研高分子材料股份有限公司 2022-03-25 CN disclosed
CN-101346648-B Photochromic materials with electron-withdrawing substituents TRANSITIONS OPTICAL INC 2011-07-06 CN disclosed
CN-101346648-A Photochromic materials with electron-withdrawing substituents TRANSITIONS OPTICAL INC (US) 2009-01-14 CN disclosed
CN-100372877-C High molecular type diphenyl ketone light initiator and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2008-03-05 CN disclosed
CN-100372875-C High molecular benzophenone photoinitiator and its prepn process UNIV SHANGHAI JIAOTONG (CN) 2008-03-05 CN disclosed
CN-100360504-C Sulfur-containing, polymerizable benzophenone photoinitiator and preparation method thereof UNIV SHANGHAI JIAOTONG (CN) 2008-01-09 CN disclosed
CN-1858078-A High molecular type diphenyl ketone light initiator and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-11-08 CN disclosed
CN-1847275-A High molecular benzophenone photoinitiator and its prepn process UNIV SHANGHAI JIAOTONG (CN) 2006-10-18 CN disclosed
CN-1789245-A Sulfur-containing, polymerizable benzophenone photoinitiator and preparation method thereof UNIV SHANGHAI JIAOTONG (CN) 2006-06-21 CN disclosed
CN-1727335-A Photoinitiator of benzophenone containing N-phenyl maleimide base group, and preparation method UNIV SHANGHAI JIAOTONG (CN) 2006-02-01 CN disclosed
US-5817698-A Substituted cycloalkylamine derivatives and their use as calcium channel antagonists SMITHKLINE BEECHAM PLC (GB) 1998-10-06 US disclosed