Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 12/20 | 0.62 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 6/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.43 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420574 | 1.00 | MMP3 (0.62) | MMP3CTSLCTSBCTSSCTSK | |
| SCHEMBL6961003 | 0.83 | MMP3 (0.65) | MMP3CTSSCA1CA2CA9 | |
| SCHEMBL6960997 | 0.83 | MMP3 (0.65) | MMP3CTSSCA1CA2CA9 | |
| SCHEMBL7423362 | 0.81 | MMP3 (0.67) | MMP3CA1CA2CA9MMP1 | |
| SCHEMBL7423375 | 0.81 | MMP3 (0.67) | MMP3CA1CA2CA9MMP1 | |
| SCHEMBL6957813 | 0.80 | MMP3 (0.46) | MMP3CA1CA2CA9MMP1 | |
| SCHEMBL6961636 | 0.79 | CTSK (0.59) | MMP3CTSLCTSBCTSSCTSK | |
| SCHEMBL6961631 | 0.79 | CTSK (0.59) | MMP3CTSLCTSBCTSSCTSK | |
| SCHEMBL6965221 | 0.77 | CA1 (0.44) | MMP3CA1CA2CA9MMP1 | |
| SCHEMBL6961552 | 0.76 | MMP3 (0.64) | MMP3CTSSCTSKCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |