Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951205 | 0.81 | HTR1A (0.51) | KDM4EALDH1A1MAPTHPGDHTT | |
| SCHEMBL16132602 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1MAPTHPGDHTT | |
| SCHEMBL9951909 | 0.79 | MEN1 (0.55) | KDM4EALDH1A1MAPTHPGDHTT | |
| SCHEMBL2854918 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL2851009 | 0.77 | PDE10A (0.41) | ALDH1A1HPGDHTTHDAC1HDAC2 | |
| SCHEMBL16106608 | 0.77 | HDAC3 (0.49) | KDM4EALDH1A1MAPTHPGDHTT | |
| SCHEMBL16106664 | 0.77 | HDAC3 (0.49) | KDM4EALDH1A1MAPTHPGDHTT | |
| SCHEMBL16106565 | 0.77 | HDAC3 (0.49) | KDM4EALDH1A1MAPTHPGDHTT | |
| SCHEMBL16106558 | 0.77 | HDAC3 (0.49) | KDM4EALDH1A1MAPTHPGDHTT | |
| SCHEMBL16106388 | 0.77 | HDAC3 (0.49) | KDM4EALDH1A1MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026933-A1 | SUBSTITUTED AMIDINOARYL DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |