Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636344 | 0.88 | SRC (0.52) | CA1CA2NPC1RAB9ASRC | |
| SCHEMBL638265 | 0.87 | SRC (0.51) | CA1CA2NPC1RAB9ASRC | |
| SCHEMBL2818914 | 0.81 | SRC (0.55) | CA1CA2NPC1RAB9ASRC | |
| SCHEMBL7422566 | 0.81 | NFE2L2 (0.56) | NPC1RAB9ATRPM8MAPTNFE2L2 | |
| SCHEMBL5302703 | 0.80 | ALDH1A1 (0.50) | SRCPOLBALDH1A1HPGDPDE4B | |
| SCHEMBL11779563 | 0.79 | SRC (0.49) | SRCPOLBALDH1A1HPGDLMNA | |
| SCHEMBL29343997 | 0.79 | ALDH1A1 (0.52) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL31092856 | 0.79 | ALDH1A1 (0.52) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL2368349 | 0.78 | DRD1 (0.40) | SRCPOLBHPGDPDE4BPDE4A | |
| O-Veratraldehyde SCHEMBL29923149 | 0.78 | SRC (0.67) | CA1CA2NPC1RAB9ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766676-A4 | COMPOUNDS FOR AND METHOD OF INHIBITING PHOSPHODIESTERASE IV | EURO CELTIQUE SA (LU) | 1998-07-08 | — | — | EP | disclosed |
| EP-0766676-A1 | COMPOUNDS FOR AND METHOD OF INHIBITING PHOSPHODIESTERASE IV | Euroceltique S.A. (LU) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996000218-A1 | COMPOUNDS FOR AND METHOD OF INHIBITING PHOSPHODIESTERASE IV | EURO-CELTIQUE, S.A. (LU) | 1996-01-04 | — | — | WO | disclosed |