Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 6/20 | 0.47 |
| ▸ | PYGM | P11217 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847641 | 1.00 | PYGL (0.47) | PYGLPYGMEPHX2GAARIPK1 | |
| SCHEMBL13878889 | 0.86 | EPHX2 (0.46) | PYGLPYGMEPHX2GAANFKB1 | |
| SCHEMBL4072157 | 0.86 | EPHX2 (0.46) | PYGLPYGMEPHX2GAANFKB1 | |
| SCHEMBL13783989 | 0.84 | GAA (0.43) | PYGLPYGMEPHX2GAARIPK1 | |
| SCHEMBL1270295 | 0.83 | RIPK1 (0.58) | PYGLPYGMEPHX2GAARIPK1 | |
| SCHEMBL1270296 | 0.83 | RIPK1 (0.58) | PYGLPYGMEPHX2GAARIPK1 | |
| SCHEMBL4806148 | 0.83 | EPHX2 (0.63) | PYGLPYGMEPHX2GAANFKB1 | |
| SCHEMBL651278 | 0.83 | EPHX2 (0.63) | PYGLPYGMEPHX2GAANFKB1 | |
| SCHEMBL29900496 | 0.83 | EPHX2 (0.63) | PYGLPYGMEPHX2GAANFKB1 | |
| SCHEMBL651277 | 0.83 | EPHX2 (0.63) | PYGLPYGMEPHX2GAANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |