Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905884 | 0.91 | TAAR1 (0.57) | AOC3L3MBTL1CASRMTNR1AMTNR1B | |
| SCHEMBL2806820 | 0.84 | HTR2A (0.62) | AOC3L3MBTL1CASRMTNR1AMTNR1B | |
| SCHEMBL6001101 | 0.81 | MTNR1A (0.55) | AOC3L3MBTL1CASRMTNR1AMTNR1B | |
| SCHEMBL11081355 | 0.80 | AOC3 (0.54) | AOC3L3MBTL1CASRMTNR1AMTNR1B | |
| SCHEMBL7416098 | 0.80 | AOC3 (0.38) | AOC3L3MBTL1CASRTAAR1MAOB | |
| SCHEMBL7410361 | 0.79 | ACHE (0.42) | TAAR1HTR2AMAOBALDH1A1 | |
| SCHEMBL410128 | 0.79 | TAAR1 (0.53) | AOC3L3MBTL1CASRTAAR1HTR2A | |
| SCHEMBL413321 | 0.79 | TAAR1 (0.53) | AOC3L3MBTL1CASRTAAR1HTR2A | |
| SCHEMBL1473114 | 0.79 | AOC3 (0.53) | AOC3L3MBTL1CASRTAAR1ALDH1A1 | |
| SCHEMBL30835582 | 0.78 | FGFR2 (0.44) | AOC3L3MBTL1CASRMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | disclosed |