Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.61 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418708 | 0.78 | GBA1 (0.67) | GBA1PTK2SSTR4SSTR2MAPK1 | |
| SCHEMBL10654616 | 0.76 | GBA1 (1.00) | GBA1RAD52SSTR4SSTR2MAPK1 | |
| SCHEMBL27944767 | 0.75 | PTK2 (0.60) | GBA1PTK2NCF1NPC1MAPK1 | |
| SCHEMBL5943598 | 0.74 | NCF1 (0.52) | GBA1PTK2NCF1NPC1MAPT | |
| SCHEMBL5943623 | 0.71 | NCF1 (0.58) | PTK2NCF1MAPT | |
| SCHEMBL22775885 | 0.70 | PTK2 (0.58) | PTK2NCF1NPC1MAPTRAB9A | |
| SCHEMBL14980561 | 0.69 | PTK2 (1.00) | GBA1PTK2NCF1NPC1MAPT | |
| SCHEMBL25488411 | 0.67 | NCF1 (0.56) | PTK2NCF1MAPTMAPK1 | |
| SCHEMBL10457122 | 0.67 | NCF1 (0.52) | PTK2NCF1NPC1MAPTMAPK1 | |
| SCHEMBL10652605 | 0.66 | GBA1 (0.66) | GBA1PTK2SSTR4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019050-B1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK AS (DK) | 2002-03-20 | — | — | EP | disclosed |
| US-6159941-A | Use of somatostatin agonists and antagonists for treating diseases related to the eye | NOVO NORDISK A/S (DK) | 2000-12-12 | — | — | US | disclosed |
| US-6127343-A | SELECTIVE, COMPETITIVE SOMATOSTATIN RECEPTOR LIGANDS OF NONPEPTIDE ORIGIN, FOR MEDIATING THE BIOLOGICAL EFFECT OF SOMATOSTATIN AGONISTS OR ANTAGONIST | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| EP-1019050-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 2000-07-19 | — | — | EP | disclosed |
| EP-0912551-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998058646-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 1998-12-30 | — | — | WO | disclosed |
| WO-1997043278-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1997-11-20 | — | — | WO | disclosed |