Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140914 | 0.82 | MAPT (0.57) | MAPTALDH1A1GAATSHRKDM4E | |
| SCHEMBL28815680 | 0.81 | RAB9A (0.45) | ALDH1A1GAAHTTTDP1CYP2C19 | |
| SCHEMBL4682191 | 0.80 | MAPT (0.62) | MAPTALDH1A1GAATSHRKDM4E | |
| SCHEMBL30853462 | 0.80 | MAPT (0.62) | MAPTALDH1A1GAATSHRKDM4E | |
| SCHEMBL4136786 | 0.79 | PTGS1 (0.44) | MAPTALDH1A1GAATSHRKDM4E | |
| SCHEMBL30303082 | 0.78 | MAPT (0.44) | MAPTALDH1A1GAATSHRKDM4E | |
| SCHEMBL28917764 | 0.78 | MAPT (0.44) | MAPTALDH1A1GAATSHRKDM4E | |
| SCHEMBL13588584 | 0.76 | GAA (0.52) | MAPTALDH1A1GAATSHRKDM4E | |
| SCHEMBL5778799 | 0.76 | MAPT (0.54) | MAPTALDH1A1GAATSHRKDM4E | |
| SCHEMBL5778803 | 0.76 | MAPT (0.54) | MAPTALDH1A1GAATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |