Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853462 | 1.00 | MAPT (0.62) | MAPTKDM4EALDH1A1ALOX15CYP2C9 | |
| SCHEMBL29995197 | 0.84 | MAPT (0.68) | MAPTKDM4EALDH1A1ALOX15CYP2C9 | |
| SCHEMBL45146 | 0.84 | MAPT (0.68) | MAPTKDM4EALDH1A1ALOX15CYP2C9 | |
| Hydrochloric Acid SCHEMBL1856980 | 0.83 | MAPT (0.66) | MAPTKDM4EALDH1A1ALOX15CYP2C9 | |
| SCHEMBL16585812 | 0.82 | MAPT (0.60) | MAPTKDM4EALDH1A1GAALMNA | |
| SCHEMBL30955004 | 0.82 | MAPT (0.60) | MAPTKDM4EALDH1A1GAALMNA | |
| SCHEMBL7420967 | 0.80 | MAPT (0.52) | MAPTKDM4EALDH1A1ALOX15CYP2C9 | |
| SCHEMBL29968115 | 0.80 | JAK2 (0.51) | MAPTKDM4EALDH1A1ALOX15CYP2C9 | |
| SCHEMBL3872066 | 0.80 | JAK2 (0.51) | MAPTKDM4EALDH1A1ALOX15CYP2C9 | |
| SCHEMBL30718459 | 0.80 | MAPT (0.54) | MAPTKDM4EALDH1A1ALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12486251-B2 | CBP/EP300 inhibitor and use thereof | PHARMABLOCK SCIENCES (NANJING) , INC. (CN) | 2025-12-02 | — | — | US | disclosed |
| CN-115397822-B | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-20230159497-A1 | CBP/EP300 INHIBITOR AND USE THEREOF | PHARMABLOCK SCIENCES (NANJING) , INC. (CN) | 2023-05-25 | — | — | US | disclosed |
| EP-4140996-A1 | CBP/EP300 INHIBITOR AND USE THEREOF | PHARMABLOCK SCIENCES (NANJING), INC. (CN) | 2023-03-01 | — | — | EP | disclosed |
| CN-115397822-A | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-105189461-B | The dibasic 1- acyl groups -4- amino -1,2,3,4- tetrahydroquinoline derivatives of 2,3- and their purposes as bromine domain inhibitor | 葛兰素史克知识产权第二有限公司 | 2018-05-15 | — | — | CN | disclosed |
| EP-1236712-B1 | AMIDINOPHENYLPYRUVIC ACID DERIVATIVE | AJINOMOTO KK (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-6710056-B2 | PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVE AN EXCELLENT ANTAGONISTIC EFFECT AGAINST ACTIVATED BLOOD COAGULATION FACTOR VII. | AJINOMOTO CO., INC. (JP) | 2004-03-23 | — | — | US | disclosed |
| US-20030232868-A1 | Cyclic carboxylic acids as integrin antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-18 | — | — | US | disclosed |
| US-20030109547-A1 | Amidinophenylpyruvic acid derivatives | AJINOMOTO CO. INC (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-1276714-A2 | CYCLIC CARBOXYLIC ACIDS AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2003-01-22 | — | — | EP | disclosed |
| EP-1236712-A1 | AMIDINOPHENYLPYRUVIC ACID DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001081298-A2 | CYCLIC CARBOXYLIC ACIDS AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109547-A1 | Amidinophenylpyruvic acid derivatives | HABP2, F2, F7 | MAPT 4059/4885KDM4E 2614/4885ALDH1A1 622/4885 |
| US-20230159497-A1 | CBP/EP300 INHIBITOR AND USE THEREOF | EP300, CREBBP, BPTF | MAPT 2797/4885KDM4E 440/4885ALDH1A1 2314/4885 |
| US-20030232868-A1 | Cyclic carboxylic acids as integrin antagonists | ITGA1, ITGB1, ITGA2B | MAPT 4196/4885KDM4E 3757/4885ALDH1A1 316/4885 |
| US-12486251-B2 | CBP/EP300 inhibitor and use thereof | EP300, CREBBP, BPTF | MAPT 2797/4885KDM4E 440/4885ALDH1A1 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.