SCHEMBL74210

SCHEMBL74210

CCCN1[CH]C=CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1375028 0.86 ALDH1A1 (0.35)
SCHEMBL24525602 0.86 ALDH1A1 (0.35)
SCHEMBL1132826 0.83 NPC1 (0.34)
SCHEMBL10379020 0.81 PTGS1 (0.36)
SCHEMBL27714664 0.79 ALDH1A1 (0.32)
SCHEMBL546776 0.78
SCHEMBL6940866 0.74
SCHEMBL4269999 0.70 ALDH1A1 (0.39)
SCHEMBL7204901 0.68 NPC1 (0.41)
SCHEMBL13975662 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102083863-B Improved controlled radical polymerization process CARNEGIE MELLON UNIVERSITY (US) 2014-10-22 CN disclosed
CN-1805985-B Polyurethane dispersants LUBRIZOL CORP 2013-01-30 CN disclosed
CN-101157797-B Polyurethane dispersants LUBRIZOL CORP 2013-01-02 CN disclosed
US-8197847-B2 Process for making polymers and supports comprising pendant sugar side groups WARWICK EFFECT POLYMERS LTD. (GB) 2012-06-12 US disclosed
US-8129505-B2 Formed by catalytic polymerization; antibody conjugates UCB PHARMA S.A. (BE) 2012-03-06 US disclosed
EP-1926757-B1 ANTIBODY-COMB POLYMER CONJUGATE UCB PHARMA SA (BE) 2012-02-22 EP disclosed
CN-102083863-A Improved controlled radical polymerization process UNIV CARNEGIE MELLON 2011-06-01 CN disclosed
US-20090082224-A1 POLYMERS WARWICK EFFECT POLYMERS LIMITED (GB) 2009-03-26 US disclosed
US-20080220005-A1 Comb Polymers UCB PHARMA S.A. (BE) 2008-09-11 US disclosed
EP-1926757-A1 COMB POLYMERS UCB Pharma, S.A. (BE) 2008-06-04 EP disclosed
CN-101157797-A Polyurethane dispersants LUBRIZOL CORP (US) 2008-04-09 CN disclosed
WO-2007031734-A1 COMB POLYMERS UCB PHARMA S.A. (BE) 2007-03-22 WO disclosed
CN-1805985-A Polyurethane dispersants LUBRIZOL CORP (US) 2006-07-19 CN disclosed
EP-1646661-A2 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYPEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH, POLYPEPTIDE CONJUGATES AND DRUNG OBTAINED THEREFROM Warwick Effect Polymers Limited (GB) 2006-04-19 EP disclosed
WO-2004113394-A2 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYPEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH, POLYPEPTIDE CONJUGATES AND DRUGS OBTAINED THEREFROM WARWICK EFFECT POLYMERS LIMITED (GB) 2004-12-29 WO disclosed
US-20040236027-A1 Polymers having co-continuous architecture BIO-LAYER PTY. LIMITED (AU) 2004-11-25 US disclosed
EP-1368418-A1 POLYMERS HAVING CO-CONTINUOUS ARCHITECTURE Polymerat Pty Ltd (AU) 2003-12-10 EP disclosed
WO-2003040218-A1 POROUS POLYMER FILMS POLYMERAT PTY LTD (AU) 2003-05-15 WO disclosed
US-20030022994-A1 Polymers having co-continuous architecture BIO-LAYER PTY. LIMITED (AU) 2003-01-30 US disclosed
WO-2002057344-A1 POLYMERS HAVING CO-CONTINUOUS ARCHITECTURE POLYMERAT PTY LTD (AU) 2002-07-25 WO disclosed