Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409035 | 0.82 | ADRA2A (0.40) | KMT2AMEN1ALDH1A1HTR2AHTR2C | |
| SCHEMBL2066360 | 0.77 | TAAR1 (0.60) | HTR2AHTR2CHTR2BADRA2AADRA1A | |
| SCHEMBL516440 | 0.75 | ESR1 (0.48) | HTR2AHTR2CHTR2BACHEADRA2A | |
| SCHEMBL21495213 | 0.74 | IDO1 (0.56) | KMT2AMEN1HTR2APOLBIDO1 | |
| SCHEMBL2086020 | 0.74 | IDO1 (0.56) | KMT2AMEN1HTR2APOLBIDO1 | |
| SCHEMBL8755736 | 0.73 | MEN1 (0.56) | KMT2AMAPTMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL3905408 | 0.70 | TAAR1 (0.41) | KMT2AMEN1ALDH1A1HTR2AIDO1 | |
| SCHEMBL7412490 | 0.70 | TACR1 (0.46) | IDO1TDO2CACNA1C | |
| SCHEMBL28801416 | 0.69 | HTR2A (0.50) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL11873422 | 0.68 | KMT2A (0.54) | KMT2AMAPTMEN1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | disclosed |