Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 5/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.38 |
| ▸ | F2 | P00734 | 6/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7445868 | 0.88 | KLK1 (0.40) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL7446487 | 0.86 | ALDH1A1 (0.38) | NQO2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL7419106 | 0.86 | RAB9A (0.40) | NQO2RAB9ANPC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7449387 | 0.84 | RAB9A (0.40) | NQO2RAB9ANPC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7451402 | 0.84 | RAB9A (0.41) | NQO2RAB9ANPC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7455211 | 0.83 | F2 (0.41) | NQO2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL7442305 | 0.83 | F2 (0.48) | NQO2RAB9ANPC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7451053 | 0.83 | F2 (0.42) | NQO2RAB9ANPC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7449029 | 0.82 | F2 (0.47) | NQO2RAB9ANPC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7418107 | 0.82 | F2 (0.47) | NQO2RAB9ANPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244636-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | Boehringer Ingelheim Pharma KG (DE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047896-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | disclosed |