Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25413 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL27528926 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL28018139 | 0.83 | HPRT1 (0.61) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL534978 | 0.83 | HPRT1 (0.61) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL844803 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL18221939 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL268735 | 0.80 | ALDH1A1 (0.65) | CA1CA2ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL29391827 | 0.80 | ALDH1A1 (0.65) | CA1CA2ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL30186719 | 0.80 | ALDH1A1 (0.65) | CA1CA2ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL2268337 | 0.78 | CYP1A2 (0.41) | CA1CA2ALDH1A1HSD17B10CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479505-B1 | TREATING AIRWAY DISORDER IN A PATIENT COMPRISING ADMINISTERING TO SAID PATIENT IN NEED THEREOF A THERAPEUTICALLY EFFECTIVE AMOUNT OF A PHOSPHODIESTERASE IV INHIBITOR | ALTANA PHARMA AG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1147088-A1 | 6-ARYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042019-A1 | 6-ARYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-07-20 | — | — | WO | disclosed |
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |
| EP-0024282-A1 | Benzoyl derivatives, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1981-03-04 | — | — | EP | disclosed |
| US-4112114-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | SYNTEX (U.S.A.) INC. (US) | 1978-09-05 | — | — | US | disclosed |