Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274844 | 0.94 | ALDH1A1 (0.33) | CYP1A2ALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL2271084 | 0.88 | ALDH1A1 (0.39) | CYP1A2ALDH1A1TSHRHSD17B10CYP2A6 | |
| SCHEMBL20774103 | 0.87 | ALDH1A1 (0.46) | CYP1A2ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL28981543 | 0.86 | ALDH1A1 (0.38) | CYP1A2ALDH1A1TSHRHSD17B10CYP2A6 | |
| SCHEMBL152529 | 0.85 | CYP1A2 (0.43) | CYP1A2ALDH1A1TSHRHSD17B10CYP2A6 | |
| SCHEMBL25413 | 0.85 | ALDH1A1 (0.57) | CYP1A2ALDH1A1TSHRHSD17B10CYP2A6 | |
| SCHEMBL350813 | 0.84 | NISCH (0.31) | NISCH | |
| SCHEMBL144462 | 0.84 | TNF (0.44) | CYP1A2ALDH1A1TSHRHSD17B10CYP2A6 | |
| SCHEMBL27528926 | 0.83 | ALDH1A1 (0.55) | CYP1A2ALDH1A1TSHRHSD17B10CYP2A6 | |
| SCHEMBL21295584 | 0.82 | DHFR (0.39) | CYP1A2ALDH1A1TSHRHSD17B10CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094223-B | binaphthyl compounds | 罗伊特化学仪器制造公司 | 2023-10-27 | — | — | CN | disclosed |
| US-11072573-B2 | Binaphthyl compounds | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-07-27 | — | — | US | disclosed |
| US-20200354299-A1 | BINAPHTHYL COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-11-12 | — | — | US | disclosed |
| EP-3676239-A1 | BINAPHTHYL COMPOUNDS | Reuter Chemische Apparatenbau e.K. (DE) | 2020-07-08 | — | — | EP | disclosed |
| CN-111094223-A | Binaphthyl compounds | 罗伊特化学仪器制造公司 | 2020-05-01 | — | — | CN | disclosed |
| WO-2019043060-A1 | BINAPHTHYL COMPOUNDS | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2019-03-07 | — | — | WO | disclosed |
| US-8512878-B2 | Diaminopyrene derivative and organic EL device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20110193064-A1 | DIAMINOPYRENE DERIVATIVE AND ORGANIC EL DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354299-A1 | BINAPHTHYL COMPOUNDS | UACA, C9, C1S | CYP1A2 333/4885ALDH1A1 1476/4885TSHR 3380/4885 |
| US-11072573-B2 | Binaphthyl compounds | UACA, C9, C1S | CYP1A2 333/4885ALDH1A1 1476/4885TSHR 3380/4885 |
| US-20110193064-A1 | DIAMINOPYRENE DERIVATIVE AND ORGANIC EL DEVICE USING THE SAME | ELP1, EED, ESR1 | CYP1A2 1772/4885ALDH1A1 237/4885TSHR 4845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.