Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 12/20 | 0.47 |
| ▸ | KYAT3 | Q6YP21 | 4/20 | 0.47 |
| ▸ | KYAT1 | Q16773 | 3/20 | 0.47 |
| ▸ | GOT1 | P17174 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1239293 | 0.82 | AADAT (0.51) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL7423513 | 0.81 | AADAT (0.45) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL4801687 | 0.79 | AADAT (0.59) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL14170038 | 0.79 | AADAT (0.59) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL9198224 | 0.78 | AADAT (0.49) | AADATKYAT3KYAT1GOT1 | |
| Hydrochloric Acid SCHEMBL7416859 | 0.77 | AADAT (0.58) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL7419579 | 0.77 | AADAT (0.51) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL16613090 | 0.76 | AADAT (0.52) | AADATKYAT3KYAT1GOT1GAA | |
| SCHEMBL4071608 | 0.74 | AADAT (0.48) | AADATKYAT3KYAT1GOT1GAA | |
| SCHEMBL9200143 | 0.73 | AADAT (0.44) | AADATKYAT3KYAT1GOT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |