SCHEMBL9198224

SCHEMBL9198224

COC(CON1C(=O)[C@@H](N)Cc2ccccc21)OC

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AADAT Q8N5Z0 16/20 0.49
KYAT3 Q6YP21 4/20 0.49
KYAT1 Q16773 3/20 0.49
GOT1 P17174 1/20 0.49
ANPEP P15144 1/20 0.34
NOTUM Q6P988 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7416442 0.92 AADAT (0.44) AADATKYAT3KYAT1GOT1
SCHEMBL7419579 0.87 AADAT (0.51) AADATKYAT3KYAT1GOT1ANPEP
SCHEMBL7423513 0.81 AADAT (0.45) AADATKYAT3KYAT1GOT1
SCHEMBL14170038 0.81 AADAT (0.59) AADATKYAT3KYAT1GOT1ANPEP
SCHEMBL4801687 0.81 AADAT (0.59) AADATKYAT3KYAT1GOT1ANPEP
Hydrochloric Acid SCHEMBL7416859 0.79 AADAT (0.58) AADATKYAT3KYAT1GOT1ANPEP
Hydrochloric Acid SCHEMBL1239293 0.79 AADAT (0.51) AADATKYAT3KYAT1GOT1ANPEP
SCHEMBL7422259 0.78 AADAT (0.47) AADATKYAT3KYAT1GOT1
SCHEMBL16613090 0.77 AADAT (0.52) AADATKYAT3KYAT1GOT1ANPEP
SCHEMBL9200143 0.75 AADAT (0.44) AADATKYAT3KYAT1GOT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641323-A1 CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-03-08 EP disclosed