Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 17/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.52 |
| ▸ | OXTR | P30559 | 4/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421754 | 0.81 | AVPR2 (0.50) | AVPR2AVPR1AOXTRP2RX7 | |
| SCHEMBL7420622 | 0.81 | AVPR2 (0.43) | AVPR2AVPR1AOXTR | |
| SCHEMBL7424272 | 0.77 | AVPR2 (0.50) | AVPR2AVPR1AOXTR | |
| SCHEMBL7421267 | 0.76 | AVPR2 (0.38) | AVPR2AVPR1AOXTR | |
| SCHEMBL7422025 | 0.74 | AVPR2 (0.42) | AVPR2AVPR1AOXTRP2RX7 | |
| SCHEMBL7424683 | 0.74 | AVPR2 (0.37) | AVPR2AVPR1AOXTR | |
| SCHEMBL6623356 | 0.73 | AVPR2 (0.65) | AVPR2AVPR1AOXTR | |
| SCHEMBL7404580 | 0.73 | AVPR2 (0.44) | AVPR2AVPR1AP2RX7IDH1 | |
| SCHEMBL7420705 | 0.73 | AVPR2 (0.33) | AVPR2AVPR1AIDH1 | |
| SCHEMBL7638228 | 0.73 | AVPR2 (0.57) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000062-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-17 | — | — | EP | claimed |
| WO-1999006409-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-11 | — | — | WO | claimed |