Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 15/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.40 |
| ▸ | OXTR | P30559 | 4/20 | 0.40 |
| ▸ | F9 | P00740 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7632997 | 0.88 | AVPR2 (0.41) | AVPR2AVPR1AOXTRUSP30 | |
| SCHEMBL7421754 | 0.79 | AVPR2 (0.50) | AVPR2AVPR1AOXTR | |
| SCHEMBL7420622 | 0.79 | AVPR2 (0.43) | AVPR2AVPR1AOXTR | |
| SCHEMBL7422271 | 0.77 | AVPR2 (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL7638228 | 0.74 | AVPR2 (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL7421267 | 0.74 | AVPR2 (0.38) | AVPR2AVPR1AOXTR | |
| SCHEMBL6622674 | 0.73 | AVPR2 (0.72) | AVPR2AVPR1AOXTR | |
| SCHEMBL6623658 | 0.72 | AVPR2 (0.55) | AVPR2AVPR1AOXTR | |
| SCHEMBL7422025 | 0.72 | AVPR2 (0.42) | AVPR2AVPR1AOXTR | |
| SCHEMBL7635179 | 0.71 | LMNA (0.55) | AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000062-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-17 | — | — | EP | claimed |
| WO-1999006409-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-11 | — | — | WO | claimed |