Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.37 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420705 | 0.85 | AVPR2 (0.33) | AVPR2AVPR1ASCN9AKDM4ENPC1 | |
| SCHEMBL7416534 | 0.77 | AVPR2 (0.32) | AVPR2AVPR1AOXTRKMT2A | |
| SCHEMBL5229778 | 0.77 | FFAR2 (0.42) | KMT2A | |
| SCHEMBL7424072 | 0.75 | AVPR1A (0.34) | AVPR2AVPR1ANPC1HPGDRAB9A | |
| SCHEMBL6624224 | 0.74 | AVPR1A (0.70) | AVPR2AVPR1A | |
| SCHEMBL7422271 | 0.74 | AVPR2 (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL7420578 | 0.73 | ADORA3 (0.35) | AVPR2AVPR1ANPC1HPGDRAB9A | |
| SCHEMBL7416560 | 0.73 | AVPR1A (0.36) | AVPR2AVPR1AOXTRNPC1HPGD | |
| SCHEMBL7549935 | 0.72 | BCAT2 (0.34) | AVPR2AVPR1AOXTRKDM4ENPC1 | |
| SCHEMBL7419949 | 0.72 | NR1H4 (0.35) | AVPR2AVPR1AOXTRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216045-A2 | VASOPRESSIN AGONIST FORMULATION AND PROCESS | American Cynamid Company (US) | 2002-06-26 | — | — | EP | claimed |
| WO-2001022969-A2 | VASOPRESSIN AGONIST FORMULATION AND PROCESS | AMERICAN CYNAMID COMPANY (US) | 2001-04-05 | — | — | WO | claimed |
| EP-1000062-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-17 | — | — | EP | claimed |
| WO-1999006409-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-11 | — | — | WO | claimed |